Succinimide-N-sulfonic acid: An efficient and recyclable catalyst for the one-pot synthesis of tetrahydrobenzo[c]acridine-8(7H)-one derivatives

Abstract

Synthesis of substituted 10,10-dimethyl-7-phenyl-9,10,11,12-tetrahydrobenzo[c]acridin-8(7H)-one derivatives proceeded by the one-pot reaction of aromatic aldehydes, 5,5-dimethylcyclohexane-1,3-dione (dimedone) and 1-naphthylamine, in the presence of Succinimide-N-sulfonic acid (SuSA) has been reported. Simplicity of operation, high yields, easy work-up and a wide range of substrate applicabilities are the key advantages of this methodology. Furthermore, the catalyst can be recovered conveniently and reused efficiently.

Keywords

• Succinimide-N-sulfonic acid
• Tetrahydrobenzo[c]acridine derivatives
• Multi component
• One-pot reaction