Nature Communications (Aug 2020)

A hidden gene in astroviruses encodes a viroporin

  • Valeria Lulla,
  • Andrew E. Firth

DOI
https://doi.org/10.1038/s41467-020-17906-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Astroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient production and/or release of virus particles.