Crystal structure of (3S)-3-acetoxy-17-(pyridin-3-yl)androsta-5,16-diene

Abstract

In the title compound, C26H33NO2 [systematic name: (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate], the steroid A, B, C and D rings adopt chair, half-chair, chair and envelope conformations, respectively. The flap atom of the envelope is the methine C atom fused with the C ring. In the crystal, adjacent molecules, generated by a 21 screw axis, are linked by weak C—H...O hydrogen bonds, forming a C(16) helical chain running along the c-axis direction.

Keywords

• crystal structure
• androsta-5,16-diene
• hydrogen bonds
• C(16) chain