The role of protein-derived free radicals as intermediaries of oxidative processes

Abstract

The fact that proteins are the main target of reactive species formed in the cells and extracellular fluids has led to the realization of a great deal of research devoted to revealing the molecular and biological consequences associated with the presence of intermediary protein radicals. This review article describes and comments upon the main chemical pathways involving primary proteic radicals.

Keywords

• carbonyls
• chain reactions
• protein-derived free radicals
• reactive species
• repair mechanisms