Marine Drugs (Apr 2010)

Halogenated Indole Alkaloids from Marine Invertebrates

  • Ana Helena Januário,
  • Wilson Roberto Cunha,
  • Márcio Luís Andrade e Silva,
  • Ademar Alves da Silva Filho,
  • Caio Guedes Braguine,
  • Lucas Silva Cintra,
  • Patrícia Mendonça Pauletti

DOI
https://doi.org/10.3390/md8051526
Journal volume & issue
Vol. 8, no. 5
pp. 1526 – 1549

Abstract

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This review discusses the isolation, structural elucidation, and biological activities of halogenated indole alkaloids obtained from marine invertebrates. Meridianins and related compounds (variolins, psammopemmins, and aplicyanins), as well as aplysinopsins and leptoclinidamines, are focused on. A compilation of the 13C-NMR spectral data of these selected natural indole alkaloids is also provided.

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