mSystems (Aug 2021)
Horizontal Gene Transfer Is the Main Driver of Antimicrobial Resistance in Broiler Chicks Infected with Salmonella enterica Serovar Heidelberg
- Adelumola Oladeinde,
- Zaid Abdo,
- Maximilian O. Press,
- Kimberly Cook,
- Nelson A. Cox,
- Benjamin Zwirzitz,
- Reed Woyda,
- Steven M. Lakin,
- Jesse C. Thomas,
- Torey Looft,
- Douglas E. Cosby,
- Arthur Hinton,
- Jean Guard,
- Eric Line,
- Michael J. Rothrock,
- Mark E. Berrang,
- Kyler Herrington,
- Gregory Zock,
- Jodie Plumblee Lawrence,
- Denice Cudnik,
- Sandra House,
- Kimberly Ingram,
- Leah Lariscy,
- Martin Wagner,
- Samuel E. Aggrey,
- Lilong Chai,
- Casey Ritz
Affiliations
- Adelumola Oladeinde
- ORCiD
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Zaid Abdo
- ORCiD
- Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA
- Maximilian O. Press
- ORCiD
- Phase Genomics Inc., Seattle, Washington, USA
- Kimberly Cook
- Office of National Programs, USDA-ARS, Beltsville, Maryland, USA
- Nelson A. Cox
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Benjamin Zwirzitz
- Institute of Food Safety, Food Technology and Veterinary Public Health, University of Veterinary Medicine, Vienna, Austria
- Reed Woyda
- ORCiD
- Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA
- Steven M. Lakin
- ORCiD
- Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA
- Jesse C. Thomas
- ORCiD
- Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
- Torey Looft
- National Animal Disease Center, USDA-ARS, Ames, Iowa, USA
- Douglas E. Cosby
- ORCiD
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Arthur Hinton
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Jean Guard
- ORCiD
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Eric Line
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Michael J. Rothrock
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Mark E. Berrang
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Kyler Herrington
- Medical College of Georgia, Augusta, Georgia, USA
- Gregory Zock
- Poultry Science Department, University of Georgia, Athens, Georgia, USA
- Jodie Plumblee Lawrence
- ORCiD
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Denice Cudnik
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Sandra House
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Kimberly Ingram
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Leah Lariscy
- U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA
- Martin Wagner
- Institute of Food Safety, Food Technology and Veterinary Public Health, University of Veterinary Medicine, Vienna, Austria
- Samuel E. Aggrey
- ORCiD
- Poultry Science Department, University of Georgia, Athens, Georgia, USA
- Lilong Chai
- ORCiD
- Poultry Science Department, University of Georgia, Athens, Georgia, USA
- Casey Ritz
- ORCiD
- Poultry Science Department, University of Georgia, Athens, Georgia, USA
- DOI
- https://doi.org/10.1128/mSystems.00729-21
- Journal volume & issue
-
Vol. 6,
no. 4
Abstract
The reported increase in antibiotic-resistant bacteria in humans has resulted in a major shift away from antibiotic use in food animal production. This shift has been driven by the assumption that removing antibiotics will select for antibiotic susceptible bacterial taxa, which in turn will allow the currently available antibiotic arsenal to be more effective.
