Simple and Practical Method for the Quantitative High-Sensitivity Analysis of N‑Nitroso Duloxetine in Duloxetine Drug Products Utilizing LC-MS/MS

• Shohei Fukuda,
• Yumiko Nakase,
• Kazuhide Imagaki,
• Kanako Kondo,
• Takahiko Taniguchi,
• Osamu Uchikawa

Affiliations

Shohei Fukuda

R&D Division, Analytical Technology Unit, API Analytical Development Department, Towa Pharmaceutical Co., Ltd., Amagasaki, Hyogo, Japan

Yumiko Nakase

R&D Division, Analytical Technology Unit, API Analytical Development Department, Towa Pharmaceutical Co., Ltd., Kadoma, Osaka, Japan

Kazuhide Imagaki

R&D Division, Analytical Technology Unit, API Analytical Development Department, Towa Pharmaceutical Co., Ltd., Kadoma, Osaka, Japan

Kanako Kondo

R&D Division, Analytical Technology Unit, API Analytical Development Department, Towa Pharmaceutical Co., Ltd., Kadoma, Osaka, Japan

Takahiko Taniguchi

Towa Pharmaceutical Co., Ltd., Kadoma, Osaka, Japan

Osamu Uchikawa

Towa Pharmaceutical Co., Ltd., Kadoma, Osaka, Japan