Indole-3-acetamides: As Potential Antihyperglycemic and Antioxidant Agents; Synthesis, In Vitro α‑Amylase Inhibitory Activity, Structure–Activity Relationship, and In Silico Studies

• Kanwal,
• Khalid Mohammed Khan,
• Sridevi Chigurupati,
• Farman Ali,
• Munissa Younus,
• Maha Aldubayan,
• Abdul Wadood,
• Huma Khan,
• Muhammad Taha,
• Shahnaz Perveen

Affiliations

Kanwal

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Khalid Mohammed Khan

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Sridevi Chigurupati

Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraidah, Saudi Arabia

Farman Ali

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Munissa Younus

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Maha Aldubayan

Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraidah, Saudi Arabia

Abdul Wadood

Department of Biochemistry, Computational Medicinal Chemistry Laboratory, UCSS, Abdul Wali Khan University, Mardan, Pakistan

Huma Khan

Department of Biochemistry, Computational Medicinal Chemistry Laboratory, UCSS, Abdul Wali Khan University, Mardan, Pakistan

Muhammad Taha

Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

Shahnaz Perveen

PCSIR Laboratories Complex, Karachi, Karachi, Pakistan