Frontiers in Endocrinology (Jan 2023)

Longer physical exercise duration prevents abnormal fasting plasma glucose occurrences in the third trimester: Findings from a cohort of women with gestational diabetes mellitus in Shanghai

  • Rui Zhang,
  • Xiangjin Gao,
  • Ting Sun,
  • Huan Li,
  • Qing Yang,
  • Bin Li,
  • Dongshan Zhu,
  • Ruiping Wang,
  • Ruiping Wang

DOI
https://doi.org/10.3389/fendo.2023.1054153
Journal volume & issue
Vol. 14

Abstract

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ObjectiveThis study aims to investigate the relationship between daily physical exercise (PE) duration and frequency of abnormal plasma glucose (PG) times both during fasting and 2 h after a standard diet in women with gestational diabetes mellitus (GDM).MethodsWe established a cohort involving 878 GDM women. GDM was confirmed by a diagnostic 75-g oral glucose tolerance test. Information was extracted from the delivery records and antenatal checkup forms. Physical exercise information was collected through a questionnaire.ResultsOver 80% of GDM women were under 35 years old. An abnormal fasting PG with ≥1 occurrence presented in 742/878 (84.51%), and the abnormal PG 2 h after standard diet with ≥1 occurrence presented in 634/878 (72.21%). Compared to GDM women with ≥4 occurrences of abnormal fasting PG, GDM women with 0 occurrences (odds ratio (OR) = 2.56), one occurrence (OR = 1.94), two occurrences (OR = 2.29), and three occurrences (OR = 2.16) had a higher proportion of PE duration being in the 45–60-min/day group than those in the <45-min/day group, and GDM women also had a higher proportion of PE during being in the 61–90- and >90-min/day group than those in the <45-min/day group. However, the duration of PE was not associated to the number of abnormal PG occurrences 2-h after the standard diet.ConclusionModerate-intensity PE duration in GDM women was negatively associated with the number of abnormal fasting PG occurrences but not with the number of PG occurrences 2 h after the standard diet.

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