Nature Communications (Mar 2021)
A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
- Alain Townsend,
- Pramila Rijal,
- Julie Xiao,
- Tiong Kit Tan,
- Kuan-Ying A. Huang,
- Lisa Schimanski,
- Jiandong Huo,
- Nimesh Gupta,
- Rolle Rahikainen,
- Philippa C. Matthews,
- Derrick Crook,
- Sarah Hoosdally,
- Susanna Dunachie,
- Eleanor Barnes,
- Teresa Street,
- Christopher P. Conlon,
- John Frater,
- Carolina V. Arancibia-Cárcamo,
- Justine Rudkin,
- Nicole Stoesser,
- Fredrik Karpe,
- Matthew Neville,
- Rutger Ploeg,
- Marta Oliveira,
- David J. Roberts,
- Abigail A. Lamikanra,
- Hoi Pat Tsang,
- Abbie Bown,
- Richard Vipond,
- Alexander J. Mentzer,
- Julian C. Knight,
- Andrew J. Kwok,
- Gavin R. Screaton,
- Juthathip Mongkolsapaya,
- Wanwisa Dejnirattisai,
- Piyada Supasa,
- Paul Klenerman,
- Christina Dold,
- J. Kenneth Baillie,
- Shona C. Moore,
- Peter J. M. Openshaw,
- Malcolm G. Semple,
- Lance C. W. Turtle,
- Mark Ainsworth,
- Alice Allcock,
- Sally Beer,
- Sagida Bibi,
- Donal Skelly,
- Lizzy Stafford,
- Katie Jeffrey,
- Denise O’Donnell,
- Elizabeth Clutterbuck,
- Alexis Espinosa,
- Maria Mendoza,
- Dominique Georgiou,
- Teresa Lockett,
- Jose Martinez,
- Elena Perez,
- Veronica Gallardo Sanchez,
- Giuseppe Scozzafava,
- Alberto Sobrinodiaz,
- Hannah Thraves,
- Etienne Joly
Affiliations
- Alain Townsend
- MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital
- Pramila Rijal
- MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital
- Julie Xiao
- MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital
- Tiong Kit Tan
- MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital
- Kuan-Ying A. Huang
- Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University
- Lisa Schimanski
- MRC Human Immunology Unit, MRC Weatherall Institute, John Radcliffe Hospital
- Jiandong Huo
- Structural Biology, The Rosalind Franklin Institute
- Nimesh Gupta
- Vaccine Immunology Laboratory, National Institute of Immunology
- Rolle Rahikainen
- Department of Biochemistry, University of Oxford
- Philippa C. Matthews
- Department of Microbiology and Infectious Diseases, John Radcliffe Hospital
- Derrick Crook
- Department of Microbiology and Infectious Diseases, John Radcliffe Hospital
- Sarah Hoosdally
- Nuffield Department of Medicine, University of Oxford
- Susanna Dunachie
- Nuffield Department of Medicine, University of Oxford
- Eleanor Barnes
- Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital
- Teresa Street
- Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital
- Christopher P. Conlon
- Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital
- John Frater
- Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital
- Carolina V. Arancibia-Cárcamo
- Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital
- Justine Rudkin
- Nuffield Department of Population Health, Big Data Institute, University of Oxford
- Nicole Stoesser
- Department of Microbiology and Infectious Diseases, John Radcliffe Hospital
- Fredrik Karpe
- Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital
- Matthew Neville
- Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford
- Rutger Ploeg
- Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital
- Marta Oliveira
- Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital
- David J. Roberts
- NHS Blood and Transplant, John Radcliffe Hospital
- Abigail A. Lamikanra
- NHS Blood and Transplant, John Radcliffe Hospital
- Hoi Pat Tsang
- NHS Blood and Transplant, John Radcliffe Hospital
- Abbie Bown
- Public Health England
- Richard Vipond
- Public Health England
- Alexander J. Mentzer
- Wellcome Centre for Human Genetics, University of Oxford
- Julian C. Knight
- Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford
- Andrew J. Kwok
- Wellcome Centre for Human Genetics, University of Oxford
- Gavin R. Screaton
- Wellcome Centre for Human Genetics, University of Oxford
- Juthathip Mongkolsapaya
- Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford
- Wanwisa Dejnirattisai
- Wellcome Centre for Human Genetics, University of Oxford
- Piyada Supasa
- Wellcome Centre for Human Genetics, University of Oxford
- Paul Klenerman
- Nuffield Department of Medicine, University of Oxford
- Christina Dold
- Oxford Vaccine Group, Department of Paediatrics, University of Oxford
- J. Kenneth Baillie
- Genetics and Genomics, Roslin Institute, University of Edinburgh
- Shona C. Moore
- NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool
- Peter J. M. Openshaw
- National Heart and Lung Institute, Faculty of Medicine, Imperial College London
- Malcolm G. Semple
- NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool
- Lance C. W. Turtle
- NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool
- Mark Ainsworth
- Oxford University Hospitals NHS Foundation Trust
- Alice Allcock
- Wellcome Centre for Human Genetics, University of Oxford
- Sally Beer
- Oxford University Hospitals NHS Foundation Trust
- Sagida Bibi
- Oxford Vaccine Group, Department of Paediatrics, University of Oxford
- Donal Skelly
- Oxford University Hospitals NHS Foundation Trust
- Lizzy Stafford
- Oxford University Hospitals NHS Foundation Trust
- Katie Jeffrey
- Oxford University Hospitals NHS Foundation Trust
- Denise O’Donnell
- Oxford University Hospitals NHS Foundation Trust
- Elizabeth Clutterbuck
- Oxford Vaccine Group, Department of Paediatrics, University of Oxford
- Alexis Espinosa
- Oxford University Hospitals NHS Foundation Trust
- Maria Mendoza
- Oxford University Hospitals NHS Foundation Trust
- Dominique Georgiou
- Oxford University Hospitals NHS Foundation Trust
- Teresa Lockett
- Oxford University Hospitals NHS Foundation Trust
- Jose Martinez
- Oxford University Hospitals NHS Foundation Trust
- Elena Perez
- Oxford University Hospitals NHS Foundation Trust
- Veronica Gallardo Sanchez
- Oxford University Hospitals NHS Foundation Trust
- Giuseppe Scozzafava
- Oxford University Hospitals NHS Foundation Trust
- Alberto Sobrinodiaz
- Oxford University Hospitals NHS Foundation Trust
- Hannah Thraves
- Oxford University Hospitals NHS Foundation Trust
- Etienne Joly
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS
- DOI
- https://doi.org/10.1038/s41467-021-22045-y
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 12
Abstract
Serological detection of antibodies against SARS-CoV-2 can help establish rates of seroconversion. Here the authors develop a red cell agglutination test to detect antibodies against the receptor binding domain for distribution free of charge to qualified research groups.
