Artificial Intelligence Chemistry (Jun 2024)

Automated Intelligent Platforms for High‐Throughput Chemical Synthesis

  • Jia-Min Lu,
  • Jian-Zhang Pan,
  • Yi-Ming Mo,
  • Qun Fang

Journal volume & issue
Vol. 2, no. 1
p. 100057

Abstract

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Automation and high-throughput techniques provide a solid technical foundation for realizing the deep fusion of artificial intelligence and chemistry as well as the full utilization of their advantages. In recent years, with the unique advantages of low consumption, low risk, high efficiency, high reproducibility, high flexibility and good versatility, intelligent automated platforms for high-throughput chemical synthesis aroused widespread concerns of synthetic chemists. In this review, the automated high-throughput chemical synthesis, automated high-throughput sample treatment and characterization technique, as well as the application of artificial intelligence technique in chemical synthesis are introduced. The characteristics of the systems and platforms based on these techniques, including the iChemFoundry platform developed in the ZJU-Hangzhou Global Scientific and Technological Innovation Center, are introduced. The intelligent automated platforms for high-throughput chemical synthesis will reshape the thinking mode of traditional disciplines, promote the innovation of disruptive techniques, redefine the rate of chemical synthesis, and innovate the way of material manufacturing.

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