Nature Communications (Oct 2018)
Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development
- Jinhua Liu,
- Yapu Li,
- Jingyuan Tong,
- Jie Gao,
- Qing Guo,
- Lingling Zhang,
- Bingrui Wang,
- Hui Zhao,
- Hongtao Wang,
- Erlie Jiang,
- Ryo Kurita,
- Yukio Nakamura,
- Osamu Tanabe,
- James Douglas Engel,
- Emery H. Bresnick,
- Jiaxi Zhou,
- Lihong Shi
Affiliations
- Jinhua Liu
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Yapu Li
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Jingyuan Tong
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Jie Gao
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Qing Guo
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Lingling Zhang
- Tianjin Key Laboratory of Food and Biotechnology, School of Biotechnology and Food Science, Tianjin University of Commerce
- Bingrui Wang
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Hui Zhao
- Tianjin Key Laboratory of Food and Biotechnology, School of Biotechnology and Food Science, Tianjin University of Commerce
- Hongtao Wang
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Erlie Jiang
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Ryo Kurita
- Japanese Red Cross Society, Department of Research and Development, Central Blood Institute
- Yukio Nakamura
- RIKEN BioResource Research Center, Cell Engineering Division
- Osamu Tanabe
- Department of Integrative Genomics Tohoku Medical Megabank, Tohoku University
- James Douglas Engel
- Department of Cell and Developmental Biology, University of Michigan Medical School
- Emery H. Bresnick
- Wisconsin Institutes for Medical Research, Paul Carbone Cancer Center, Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health
- Jiaxi Zhou
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- Lihong Shi
- State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
- DOI
- https://doi.org/10.1038/s41467-018-06883-x
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 15
Abstract
LncRNAs modulate diverse physiological cellular processes, however, their involvement in heme-dependent processes are not yet clear. Here the authors reveal the role of lncRNA UCA1 in erythroid cell development.
