Hellenic Journal of Cardiology (Nov 2021)

Clinical characteristics and management of patients with diabetes mellitus and stable coronary artery disease in daily clinical practice. The SCAD–DM Registry

  • Maria E. Marketou,
  • Charalambos Vlachopoulos,
  • George Hahalis,
  • Kristalenia Kafkala,
  • Nikolaos Kouvelas,
  • Ioannis Mantas,
  • Antonios Sideris,
  • Evaggelos Pisimisis,
  • Emmanouel P. Vardas,
  • Stylianos Tzeis,
  • Panos E. Vardas,
  • Vassiliki Dimitroula,
  • Christos Hatjielefteriou,
  • Nikolaos Kampouridis,
  • Georgios Karakostas,
  • Athanasios Karanasios,
  • Stylianos Lambropoulos,
  • Fotios Papalisandrou,
  • Emmanouil Scoubourdis,
  • Nikolaos Smirnioudis,
  • Eleftherios Adamopoulos,
  • Georgios Aggelopoulos,
  • Charalampos Albanis,
  • Alexandros Amaslidis,
  • Maria Andreopoulou,
  • Ilias Antoniou,
  • Ilias Apostolou,
  • Georgios Afaras,
  • Vasileios Arfaras,
  • Konstantinos Aronis,
  • Georgios Askar,
  • Christos Athanasiou,
  • Sokratis Avlonitis Antonios Beroukas,
  • Emmanouil Chorozopoulos,
  • Nikolaos Chrysomallis,
  • Konstantinos Davos,
  • Eftichia Demerouti,
  • Vasileios Dimopoulos,
  • Nikolaos Dimoulis,
  • Vasileios Drakoulidis,
  • Kiriaki Faka,
  • Dimitrios Fotiadis,
  • Alexandros Galapis,
  • Antonios Giakoumis,
  • Ioannis Goupios,
  • Christos Harbas,
  • Vasileios Hatjiioakeimidis,
  • Georgios Hondrokoukis,
  • Panagiotis Kalaras,
  • Marina Kanakaraki,
  • Konstantinos Kapetanios,
  • Vasileios Karasavvidis,
  • Theodoros Karonis,
  • Andreas Karydakis,
  • Christos Katsaris,
  • Christos Katsikas,
  • Konstantinos Katsas,
  • Sokratis Kazantzidis,
  • Nikolaos Kipouridis,
  • Eirini Kokani,
  • Georgios Kolios,
  • Ilias Konstantinidis,
  • Themistoklis Konstantinou,
  • Marios Konstantinou,
  • Georgios Kontopoulos,
  • Georgios Kontoroupis,
  • Georgios Koroniotis,
  • Apostolos Kotidis,
  • Chrysanthi Koukosi,
  • Mihail Kouremetis,
  • Christos Kouris,
  • Georgios Kouskos,
  • Konstantinos Koutras,
  • Georgios Koutsibanis,
  • Harikleia Krontira,
  • Konstantinos Lalenis,
  • Christos Liatas,
  • Leonidas Lillis,
  • Grigorios Limperatos,
  • Emmanouil Liodakis,
  • Stavros Liropoulos,
  • Ioannis Livaditis,
  • Dimitrios Logothetis,
  • Maria Lolaka,
  • Georgios Loukidelis,
  • Georgios Mablekos,
  • Antonios Manousakis,
  • Nikolaos Marinakis,
  • Dimitrios Markou,
  • Virginia Markou,
  • Anestis Matziridis,
  • Panagiotis Mavraganis,
  • Vasileios Mavridis,
  • Ioannis Mavrodimitrakis,
  • Georgios Migias,
  • Dimitrios Mitropoulos,
  • Christos Mitroulas,
  • Savvas Nikiforos,
  • Vasileios Nikolaidis,
  • Christos Nikopoulos,
  • Nikoloaos Oikonomidis,
  • Konstantinos Panagiotopoulos,
  • Georgios Panagoulias,
  • Anna Panou,
  • Ioannis Pantelakis,
  • Achilleas Papadopoulos,
  • Apostolos Papadopoulos,
  • Georgios Papaioannou,
  • Andreas Papamichail,
  • Soultana Papanastasiou,
  • Panagiotis Papas,
  • Eleftherios Papavasileiou,
  • Vasileios Papavasileiou,
  • Athanasios Patialiakas,
  • Alexandros Patsilinakos,
  • Georgios Pechlivanidis,
  • Spiridon Petrogiannis,
  • Nikolaos Pontikakis,
  • Charalampos Parissis,
  • Fotios Patsourakos,
  • Evangelos Pisimisis,
  • Andreas Pittaras,
  • Sotirios Plastiras,
  • Athanasios Platis,
  • Panagiotis Poulikarakos,
  • Markos Prionidis,
  • Paraskevi Psarogianni,
  • Emmanouil Psathakis,
  • Dimitrios Psirropoulos,
  • Maria Riga,
  • Ali Risgits,
  • Evangelos Rosmarakis,
  • Maria Samartzi,
  • Isidoros Sarris,
  • Konstantinos Sassalos,
  • Dimitrios Savvalas,
  • Georgios Siliogas,
  • David Simeonidis,
  • Loukas Sinos,
  • Andreas Skanavis,
  • Achilleas Skordas,
  • Vassiliki Sklirou,
  • Iason Skotiniotis,
  • Anastasios Spanos,
  • Dimitrios Sratech,
  • Christos Stathopoulos,
  • Rafail Stavropoulos,
  • Christos Stavrotheodoros,
  • Emmanouil Stefanakis,
  • Konstantinos Stefanis,
  • Christos Stefopoulos,
  • Dimitrios Stergiou,
  • Konstantinos Svolis,
  • Konstantinos Toulis,
  • Kallinikos Tsakonas,
  • Nikolaos Tsamis,
  • Eleni Tzamtzi-Mastaka,
  • Georgios Tzeltzes,
  • Ioannis Tsiantis,
  • Theodora Tsiotika,
  • Vasileios Vachliotis,
  • Ioannis Vakalis,
  • Konstantinos Vardakis,
  • Alexandros Vassilopoulos,
  • Georgia Vlahou,
  • Vasileios Vogas,
  • Evropia Voukelatou,
  • Nikiforos Vrettos,
  • Dionisios Xenos,
  • Konstantinos Zagoridis,
  • Tsilla Zafiriou,
  • Christos Zafiris,
  • Maria Zaharia,
  • Fanourios Zampetakis,
  • Vasileios Zouganelis

Journal volume & issue
Vol. 62, no. 6
pp. 408 – 415

Abstract

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Background: Patients with diabetes mellitus (DM) and coronary artery disease (CAD) represent a high-risk population, where comorbidities are common and the progression of coronary heart disease is relatively rapid and extensive. The present survey, conducted nationwide in a Eurozone country, Greece, with a properly organized national health system, aimed to record specific data from a significant number of patients with diabetes and documented stable CAD (SCAD). Methods and results: We conducted our survey across the country, in private and public primary, secondary, and tertiary care centers. A total of 1900 patients aged 71 ± 10 years old who suffered from both DM and chronic coronary syndromes were registered. Of the patients registered, 574 (30.24%) were women. It was found that 506 (26.6%) of the 1900 surveyed patients showed typical angina symptoms, while another 560 (29.5%) patients had developed angina-equivalent symptoms according to their history. Additionally, 324 (17%) patients had atypical symptoms that could not easily be attributed to existing CAD and the remaining 510 (26.8%) of the 1900 patients did not exhibit any angina symptoms during their daily activities. Functional testing for myocardial ischemia was not performed in 833 patients (43.8%). Myocardial scintigraphy was the most commonly used noninvasive technique (644 patients, 34%), while 492 patients (25.9%) had an exercise test and 159 (8.4%) underwent stress echocardiography. Conclusion: Real-world data in this specific high-risk population of diabetic patients with SCAD offer the opportunity to identify and improve diagnostic and therapeutic practice in the healthcare system of a European Union country.

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