Angiotensin converting enzyme inhibitors in treatment practice: similarity and difference. How to make the right choice

Abstract

The article focuses on differential choice of ACE inhibitor in clinical practice. Mechanisms of action common for all drugs in this group, indications and benefits are described. Differences in pharmacokinetic features, RAAS blockade, additional unique attributes, indications and strength of evidence for the class representative ramipril are highlighted. There is clinical data of Russian studies on anti-hypertensive effectiveness and anti-atherosclerotic properties of Hartil® (ramipril,"EGIS", Hungary).

Keywords

• hypertension
• atherosclerosis
• coronary heart disease
• stroke
• ace inhibitors
• ramipril