Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives

Abstract

Abstract A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were prepared by using click chemistry.

Keywords

• amidiaztion
• hydrazinolysis
• carbohydrazide
• carboxamide
• click chemistry