Communications Biology (Aug 2022)

Engineered endosymbionts that alter mammalian cell surface marker, cytokine and chemokine expression

  • Cody S. Madsen,
  • Ashley V. Makela,
  • Emily M. Greeson,
  • Jonathan W. Hardy,
  • Christopher H. Contag

DOI
https://doi.org/10.1038/s42003-022-03851-6
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 12

Abstract

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The establishment of non-pathogenic engineered endosymbionts through B. subtilis is presented, with the aim of delivering mammalian transcription factors to the host cell for therapeutics and research.