Nature Communications (Jul 2021)

Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells

  • Sarah M. Hücker,
  • Tobias Fehlmann,
  • Christian Werno,
  • Kathrin Weidele,
  • Florian Lüke,
  • Anke Schlenska-Lange,
  • Christoph A. Klein,
  • Andreas Keller,
  • Stefan Kirsch

DOI
https://doi.org/10.1038/s41467-021-24611-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Technologies for small non-coding RNA sequencing at the single-cell level are less mature than for sequencing mRNAs. Here the authors evaluate available protocols for analysis of circulating lung cancer tumour cells.