Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa [v2; ref status: indexed, http://f1000r.es/4n3]

Michelle R. Sanford; Anthony J. Cornel; Catelyn C. Nieman; Joao Dinis; Clare D. Marsden; Allison M. Weakley; Sarah Han; Amabelia Rodrigues; Gregory C. Lanzaro; Yoosook Lee

doi:10.12688/f1000research.5485.2

F1000Research (Nov 2014)

Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa [v2; ref status: indexed, http://f1000r.es/4n3]

Michelle R. Sanford,
Anthony J. Cornel,
Catelyn C. Nieman,
Joao Dinis,
Clare D. Marsden,
Allison M. Weakley,
Sarah Han,
Amabelia Rodrigues,
Gregory C. Lanzaro,
Yoosook Lee

Affiliations

Michelle R. Sanford: Current Affiliation: Harris County Institute of Forensic Sciences, 1885 Old Spanish Trail, Houston, 77054, USA
Anthony J. Cornel: Department of Entomology and Nematology, University of California, Davis, 95616, USA
Catelyn C. Nieman: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Joao Dinis: National Institute of Public Health (INASA), Bissau, Guinea-Bissau
Clare D. Marsden: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Allison M. Weakley: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Sarah Han: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Amabelia Rodrigues: National Institute of Public Health (INASA), Bissau, Guinea-Bissau
Gregory C. Lanzaro: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA
Yoosook Lee: Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, 95616, USA

DOI: https://doi.org/10.12688/f1000research.5485.2
Journal volume & issue: Vol. 3

Abstract

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Presence of Plasmodium falciparum circumsporozoite protein (CSP) was detected by enzyme linked immunosorbent assay (ELISA) in a sample of Anopheles gambiae s.s., A. melas and A. pharoensis collected in Guinea-Bissau during October and November 2009. The percentage of P. falciparum infected samples (10.2% overall; confidence interval (CI): 7.45-13.6%) was comparable to earlier studies from other sites in Guinea-Bissau (9.6-12.4%). The majority of the specimens collected were identified as A. gambiae which had an individual infection rate of 12.6 % (CI: 8.88-17.6) across collection sites. A small number of specimens of A. coluzzii, A. coluzzii x A. gambiae hybrids, A. melas and A. pharoensis were collected and had infection rates of 4.3% (CI:0.98-12.4), 4.1% (CI:0.35-14.5), 11.1% (CI:1.86-34.1) and 33.3% (CI:9.25-70.4) respectively. Despite being present in low numbers in indoor collections, the exophilic feeding behaviors of A. melas (N=18) and A. pharoensis (N=6) and high infection rates observed in this survey suggest falciparum-malaria transmission potential outside of the protection of bed nets.

Published in F1000Research

ISSN: 2046-1402 (Online)
Publisher: F1000 Research Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science
Website: https://f1000research.com

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