Biosensors: Electrochemical Devices—General Concepts and Performance

Abstract

This review provides a general overview of different biosensors, mostly concentrating on electrochemical analytical devices, while briefly explaining general approaches to various kinds of biosensors, their construction and performance. A discussion on how all required components of biosensors are brought together to perform analytical work is offered. Different signal-transducing mechanisms are discussed, particularly addressing the immobilization of biomolecular components in the vicinity of a transducer interface and their functional integration with electronic devices. The review is mostly addressing general concepts of the biosensing processes rather than specific modern achievements in the area.

Keywords

• enzyme-based biosensors
• electrochemical biosensors
• electron-transfer mediators
• enzyme immobilization
• signal transducers