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Disease Models & Mechanisms
(Mar 2023)
Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse
Sarah Escuin,
Saba Rose Raza-Knight,
Dawn Savery,
Carles Gaston-Massuet,
Gabriel L. Galea,
Nicholas D. E. Greene,
Andrew J. Copp
Affiliations
Sarah Escuin
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Saba Rose Raza-Knight
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Dawn Savery
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Carles Gaston-Massuet
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Gabriel L. Galea
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Nicholas D. E. Greene
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
Andrew J. Copp
Developmental Biology and Cancer Department, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK
DOI
https://doi.org/10.1242/dmm.049858
Journal volume & issue
Vol. 16, no. 3
Abstract
Read online
No abstracts available.
Keywords
embryo
neurulation
neural tube defects
actomyosin
bmp
morphogenesis
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