Reply to Holmes and Duchêne, “Can Sequence Phylogenies Safely Infer the Origin of the Global Virome?”: Deep Phylogenetic Analysis of RNA Viruses Is Highly Challenging but Not Meaningless

• Yuri I. Wolf,
• Darius Kazlauskas,
• Jaime Iranzo,
• Adriana Lucía-Sanz,
• Jens H. Kuhn,
• Mart Krupovic,
• Valerian V. Dolja,
• Eugene V. Koonin

Affiliations

Yuri I. Wolf

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA

Darius Kazlauskas

Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania

Jaime Iranzo

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA

Adriana Lucía-Sanz

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA

Jens H. Kuhn

Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, USA

Mart Krupovic

Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, Paris, France

Valerian V. Dolja

Department of Botany and Plant Pathology, Oregon State University, Corvallis, Oregon, USA

Eugene V. Koonin

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA