Journal of Pharmacy and Bioallied Sciences (Aug 2024)

Evaluation of Prevention of Initial Enamel Lesions around Orthodontic Brackets by Using Different Remineralizing Agents: An Original Research

  • Velusamy Pavethynath,
  • Bhupendra Singh Rathore,
  • N Mothi Krishna,
  • B Pragnya,
  • Ipseeta Menon,
  • Praveen K. Varma Datla,
  • Priyanka R Pujari

DOI
https://doi.org/10.4103/jpbs.jpbs_397_24
Journal volume & issue
Vol. 16, no. Suppl 3
pp. S2605 – S2607

Abstract

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Objective: The purpose of this study was to compare the efficacy of various remineralizing agents in stopping the early enamel lesions surrounding orthodontic brackets from progressing. Techniques: Four groups were randomly allocated to a total of 100 participants: the control group (no treatment), calcium phosphate, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and fluoride varnish. Remineralizing chemicals were administered in accordance with manufacturer recommendations, and enamel lesions were created around orthodontic brackets. At baseline and follow-up visits, enamel lesion development was evaluated by visual inspection, quantitative light-induced fluorescence, and microhardness tests. Results: All treatment groups showed significant improvements in microhardness and decreases in lesion size compared to the control group (P 0.05). Conclusion: Initial enamel lesions surrounding orthodontic brackets can be effectively prevented from progressing with the use of fluoride varnish, calcium phosphate, and CPP-ACP. Promising improvements in microhardness indicate that CPP-ACP may be a better treatment choice. Larger sample sizes and longer follow-up times are needed for future studies to validate these results and clarify the best strategy for maintaining the health of enamel throughout orthodontic treatment.

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