Biochemical changes in people with HIV/AIDS in the municipality of Macaé, Rio de Janeiro, Brazil

Abstract

This study aimed to characterize the lipid profile, treatment time and immune profile of people living with HIV/AIDS (PLWHA) serviced by Specialized Assistance Service (SAS) of Macaé to indentify the level of prevention according to the ecological triad. A study of transverse type, field, descriptive with 46 PLWHA of both sexes, aged between 20 to 59 years, from march to december 2017. Participated in the 26 men and 20 women research, these 91.3% resided in Macaé. The biochemical results reported changes in concetrations of triglycerides (≥150 mg dL-1) in 41.3% of PLWHA studied; 5 men and 7 women had high cholesterol (≥240 mg dL-1), however, not analyzed statistical significance. 23.9% and 19.5% of the PLWHA had maximum values of LDL-c (≥130 and ≤159 mg dL-1) and high LDL-c (≥160 mg dL-1), respectively. In addition, 26 PLWHA had HDL-c below the desirable. All participants used antiretriviral therapy, where 82.6% (n = 38) with undetectable viral load. More than half of the people (84.7%) were asymptomatic according to count of CD4+ T lymphocytes. The study identified PLWHA in the pathogenic period of secondary prevention level according ecological triad; lipid changes were found in PLWHA. Changes in lifestyle and dietary interventions can promote improvement in biochemical changes identified.