An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

Sepideh Bastani; Vahid Vahedian; Mohsen Rashidi; Amirabbas Mir; Sepideh Mirzaei; Iraj Alipourfard; Farhad Pouremamali; Hamidreza Nejabati; Jamileh kadkhoda; Nazila Fathi Maroufi; Maryam Akbarzadeh

Biomedicine & Pharmacotherapy (Sep 2022)

An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

Sepideh Bastani,
Vahid Vahedian,
Mohsen Rashidi,
Amirabbas Mir,
Sepideh Mirzaei,
Iraj Alipourfard,
Farhad Pouremamali,
Hamidreza Nejabati,
Jamileh kadkhoda,
Nazila Fathi Maroufi,
Maryam Akbarzadeh

Affiliations

Sepideh Bastani: Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran
Vahid Vahedian: Cancer Biology Research Group, Faculty of Medicine Institute of Biotechnology (FMB-IBTEC) Sao Paulo State University (UNESP), Brazil
Mohsen Rashidi: Department of Pharmacology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran; The Health of Plant and Livestock Products Research Center, Mazandaran University of Medical Sciences, Sari, Iran
Amirabbas Mir: Institute of Nano Science and Nano Technology, University of Kashan, P.O. Box 87317-51167, Kashan, Islamic Republic of Iran
Sepideh Mirzaei: Department of Biology, Faculty of Science, Islamic Azad University, Science and Research Branch, Tehran, Iran
Iraj Alipourfard: Institutitue of Biology, Biotechnology and Environmental Protection - Faculty of Natural Sciences - University of Silesia - Katowice - Poland
Farhad Pouremamali: Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Hamidreza Nejabati: Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Jamileh kadkhoda: Department of Medicinal Chemistry, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Nazila Fathi Maroufi: Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding authors.
Maryam Akbarzadeh: Department of Biochemistry, Erasmus University Medical Center, Rotterdam, the Netherlands; Corresponding authors.

Journal volume & issue: Vol. 153
p. 113297

Abstract

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Crocin, an active ingredient derived from saffron, is one of the herbal components that has recently been considered by researchers. Crocin has been shown to have many anti-inflammatory and antioxidant properties, and therefore can be used to treat various diseases. It has been shown that Crocin has a positive effect on the prevention and treatment of cardiovascular disease, cancer, diabetes, and kidney disease. In addition, the role of this substance in COVID-19 pandemic has been identified. In this review article, we tried to have a comprehensive review of the antioxidant and anti-inflammatory effects of Crocin in different diseases and different tissues. In conclusion, Crocin may be helpful in pathological conditions that are associated with inflammation and oxidative stress.

Published in Biomedicine & Pharmacotherapy

ISSN: 0753-3322 (Print); 1950-6007 (Online)
Publisher: Elsevier
Country of publisher: France
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: https://www.journals.elsevier.com/biomedicine-and-pharmacotherapy

About the journal

Abstract

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