mBio (Feb 2021)

Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract

  • Sabrina I. Green,
  • Carmen Gu Liu,
  • Xue Yu,
  • Shelley Gibson,
  • Wilhem Salmen,
  • Anubama Rajan,
  • Hannah E. Carter,
  • Justin R. Clark,
  • Xuezheng Song,
  • Robert F. Ramig,
  • Barbara W. Trautner,
  • Heidi B. Kaplan,
  • Anthony W. Maresso

DOI
https://doi.org/10.1128/mBio.03474-20
Journal volume & issue
Vol. 12, no. 1

Abstract

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Invasive pathobionts or microbes capable of causing disease can reside deep within the mucosal epithelium of our gastrointestinal tract. Targeted effective antibacterial therapies are needed to combat these disease-causing organisms, many of which may be multidrug resistant.