Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them

Abstract

It has been established that disintegrated membranes (DM) of pseudotuberculosis and intestinal Yersiniosis microbes can be used to produce highly active hyperimmune sera. Hyperimmune serum obtained as a result of immunization of rabbits with pseudotuberculosis DM showed specificity for Yersinia pseudotuberculosis cells, and serum obtained by immunization with intestinal Yersinia DM interacted in ELISA with Yersinia enterocolitica and Yersinia pseudotuberculosis cells. Antibody titers with bacterial cells of other genus of intestinal microflora were low, which allows the use of the obtained hyperimmune sera to create diagnostic yersiniosis test systems with specific and generic specificity.