Nature Communications (May 2022)

Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex

  • Sofie L. Valk,
  • Ting Xu,
  • Casey Paquola,
  • Bo-yong Park,
  • Richard A. I. Bethlehem,
  • Reinder Vos de Wael,
  • Jessica Royer,
  • Shahrzad Kharabian Masouleh,
  • Şeyma Bayrak,
  • Peter Kochunov,
  • B. T. Thomas Yeo,
  • Daniel Margulies,
  • Jonathan Smallwood,
  • Simon B. Eickhoff,
  • Boris C. Bernhardt

DOI
https://doi.org/10.1038/s41467-022-29886-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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Brain structure scaffolds intrinsic function, supporting cognition and behavioral flexibility. Here, the authors show how macroscale organization of cortical microstructure and resting-state function uncouple in transmodal cortex of humans and macaques.