226 ‘Off-the-shelf’ CD19-CAR-T cells generated from umbilical cord blood display superior anti-tumor fitness and lower pro-inflammatory activity as compared to peripheral blood-derived engineered T cells

• Mohammed Toufiq,
• Damien Chaussabel,
• Suruchi Mohan,
• Cristina Maccalli,
• Asma Al Sulaiti,
• Chiara Bonini,
• Monica Casucci,
• Chiara Cugno,
• Sara Deola,
• Mohammed El Anbari,
• Shana Jacob,
• Saroja Kotegar Balayya,
• Salim Bougarn,
• Evonne Chin-Smith,
• Alex Issam Tout,
• Neha Gopinath,
• Damilola Olagunju

Affiliations

Mohammed Toufiq

1Sidra Medicine, Doha, Qatar

Damien Chaussabel

Aff250 grid.467063.00000000403974222Sidra Medical and Research Center Doha Ad Dawhah Qatar

Suruchi Mohan

1 Obstetrics Division, Sidra Medical and Research Center, Doha, Qatar

Cristina Maccalli

Aff13 0000 0004 0397 4222grid.467063.0Department of Translational MedicineSidra Medical and Research Center Doha Qatar

Asma Al Sulaiti

1Sidra Medicine, Doha, Qatar

Chiara Bonini

2IRCCS San Raffaele Scientific Institute, Milan, Italy

Monica Casucci

1Sidra Medicine, Doha, Qatar

Chiara Cugno

2Sidra Medicine, Doha, Qatar

Sara Deola

1Sidra Medicine, Doha, Qatar

Mohammed El Anbari

1Sidra Medicine, Doha, Qatar

Shana Jacob

1Sidra Medicine, Doha, Qatar

Saroja Kotegar Balayya

1Sidra Medicine, Doha, Qatar

Salim Bougarn

1Sidra Medicine, Doha, Qatar

Evonne Chin-Smith

1Sidra Medicine, Doha, Qatar

Alex Issam Tout

1Sidra Medicine, Doha, Qatar

Neha Gopinath

1Sidra Medicine, Doha, Qatar

Damilola Olagunju

1Sidra Medicine, Doha, Qatar