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Biology Open
(Aug 2023)
A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes
Laura Schubert,
Anh T. Le,
Trista K. Hinz,
Andre C. Navarro,
Sarah K. Nelson-Taylor,
Raphael A. Nemenoff,
Lynn E. Heasley,
Robert C. Doebele
Affiliations
Laura Schubert
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Anh T. Le
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Trista K. Hinz
Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Andre C. Navarro
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Sarah K. Nelson-Taylor
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Raphael A. Nemenoff
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Lynn E. Heasley
Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Robert C. Doebele
Departments of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
DOI
https://doi.org/10.1242/bio.059994
Journal volume & issue
Vol. 12, no. 8
Abstract
Read online
No abstracts available.
Keywords
crispr
gene fusions
receptor tyrosine kinase
tyrosine kinase inhibitor
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