The relationship between vitamin D deficiency and deep vein thrombosis

Abstract

INTRODUCTION: Vitamin D is a fat-soluble vitamin that plays a role in calcium and phosphorus metabolism. Deep vein thrombosis (DVT) is an important health problem worldwide. Some researchers have reported that vitamin D supplementation reduces the risk of venous thromboembolism. The aim of our study was to evaluate vitamin D levels in patients with DVT. METHODS: This study was performed between December 2015 and December 2018. Vitamin D level measured patients during December, January, February and March were included in the study. Serum D 25 (OH) D (25-hydroxyvitamin) levels were measured to evaluate vitamin D levels of the patients. RESULTS: Our study included 58 patients with DVT whose vitamin D levels were measured. There were 27 females and 31 males, ranging in age from 15 to 85 years with a mean age of 55.8 +- -17.3 years. Vitamin D deficiency was found in 50 patients and vitamin D insufficiency found in 7 patients. The mean vitamin D level was 12.7 +- 5.0 ng / mL in male patients and 12.1 +- 7.3 ng / mL in female patients. There was no significant difference between the mean vitamin D levels of women and men (p> 0.05). DISCUSSION AND CONCLUSION: In our study, 25 (OH) D levels were found to be lower in both male and female patients with DVT. This is in line with some studies describing vitamin D deficiency as a risk factor for venous thrombosis. Furthermore, the coexistence of thrombophilic risk factors and vitamin D deficiency is likely to increase the risk of DVT.

Keywords

• vitamin d
• deep vein
• thrombosis