Advances in Laboratory Medicine (Aug 2022)

Control of occult hepatitis B virus infection

  • Lalana Garcés Marta,
  • Ortiz Pastor Oihana,
  • Solé Enrech Gemma,
  • Guerra-Ruiz Armando R.,
  • Casals Mercadal Gregori,
  • Almería Lafuente Alejandro,
  • Ballesteros Vizoso María Antonieta,
  • Medina Pablo Gabriel,
  • Salgüero Fernández Sergio,
  • Zamora Trillo Angielys,
  • Aured de la Serna Isabel,
  • Hurtado Juan Carlos,
  • Pérez-Del-Pulgar Sofía,
  • Forns Xavier,
  • Morales Ruiz Manuel

DOI
https://doi.org/10.1515/almed-2022-0065
Journal volume & issue
Vol. 3, no. 4
pp. 321 – 330

Abstract

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The diagnosis of hepatitis B virus (HBV) infection requires HBV DNA testing and serologic testing for detection of the surface antigen (HBsAg) and the hepatitis B core antibody (anti-HBc). There is a population of patients with occult HBV infection (OBI), which is not detected by HBsAg or HBV DNA quantification in blood, despite the presence of active replication in the liver.

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