Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty

Teng Fan; Jingwei He; Yonghong Wang; Jian Yu; Wen Sun

Stem Cell Research (Oct 2021)

Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty

Teng Fan,
Jingwei He,
Yonghong Wang,
Jian Yu,
Wen Sun

Affiliations

Teng Fan: Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University, Shanghai ty 201102, China
Jingwei He: Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University, Shanghai ty 201102, China
Yonghong Wang: Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University, Shanghai ty 201102, China
Jian Yu: Corresponding authors.; Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University, Shanghai ty 201102, China
Wen Sun: Corresponding authors.; Department of Traditional Chinese Medicine, Children’s Hospital of Fudan University, Shanghai ty 201102, China

Journal volume & issue: Vol. 56
p. 102542

Abstract

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Central precocious puberty (CPP) refers to a pediatric endocrine disease in which boys have secondary sexual characteristics before the age of 9 and girls before the age of 8. In this study, we generated an induced pluripotent stem cell line FDCHi006-A from the Peripheral blood cell of a typical central precocious patient who was only 7 years old. This iPSC line showed full pluripotency, normal karyotype and differentiation capacity without integrating vectors. It provides a useful model to study the underlying molecular mechanisms of CPP.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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