mSystems (Jun 2021)

Systems Analysis of Gut Microbiome Influence on Metabolic Disease in HIV-Positive and High-Risk Populations

  • Abigail J. S. Armstrong,
  • Kevin Quinn,
  • Jennifer Fouquier,
  • Sam X. Li,
  • Jennifer M. Schneider,
  • Nichole M. Nusbacher,
  • Katrina A. Doenges,
  • Suzanne Fiorillo,
  • Tyson J. Marden,
  • Janine Higgins,
  • Nichole Reisdorph,
  • Thomas B. Campbell,
  • Brent E. Palmer,
  • Catherine A. Lozupone

DOI
https://doi.org/10.1128/mSystems.01178-20
Journal volume & issue
Vol. 6, no. 3

Abstract

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The gut microbiome in people living with HIV (PLWH) is of interest since chronic infection often results in long-term comorbidities. Metabolic disease is prevalent in PLWH even in well-controlled infection and has been linked with the gut microbiome in previous studies, but little attention has been given to PLWH.