Diethyl 2,6-dimethyl-4-(naphthalen-1-yl)-1,4-dihydropyridine-3,5-dicarboxylate

Abstract

In the title compound, C23H25NO4, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The naphthalene ring system forms a dihedral angle of 88.59 (6)° with the pyridine ring. In the crystal, N—H...O and C—H...O hydrogen bonds generate an R12(6) ring motif and result in a zigzag chain along the b axis. Additional C—H...O hydrogen bonds form infinite chains along the c-axis direction.

Keywords

• crystal structure
• pyridine derivatives
• hydrogen bonds
• biological activity
• Hantzsch reaction