Nature Communications (Jun 2022)
Multimodal deep learning for Alzheimer’s disease dementia assessment
- Shangran Qiu,
- Matthew I. Miller,
- Prajakta S. Joshi,
- Joyce C. Lee,
- Chonghua Xue,
- Yunruo Ni,
- Yuwei Wang,
- Ileana De Anda-Duran,
- Phillip H. Hwang,
- Justin A. Cramer,
- Brigid C. Dwyer,
- Honglin Hao,
- Michelle C. Kaku,
- Sachin Kedar,
- Peter H. Lee,
- Asim Z. Mian,
- Daniel L. Murman,
- Sarah O’Shea,
- Aaron B. Paul,
- Marie-Helene Saint-Hilaire,
- E. Alton Sartor,
- Aneeta R. Saxena,
- Ludy C. Shih,
- Juan E. Small,
- Maximilian J. Smith,
- Arun Swaminathan,
- Courtney E. Takahashi,
- Olga Taraschenko,
- Hui You,
- Jing Yuan,
- Yan Zhou,
- Shuhan Zhu,
- Michael L. Alosco,
- Jesse Mez,
- Thor D. Stein,
- Kathleen L. Poston,
- Rhoda Au,
- Vijaya B. Kolachalama
Affiliations
- Shangran Qiu
- Department of Medicine, Boston University School of Medicine
- Matthew I. Miller
- Department of Medicine, Boston University School of Medicine
- Prajakta S. Joshi
- Department of Anatomy and Neurobiology, Boston University School of Medicine
- Joyce C. Lee
- Department of Medicine, Boston University School of Medicine
- Chonghua Xue
- Department of Medicine, Boston University School of Medicine
- Yunruo Ni
- Department of Medicine, Boston University School of Medicine
- Yuwei Wang
- Department of Medicine, Boston University School of Medicine
- Ileana De Anda-Duran
- School of Public Health and Tropical Medicine, Tulane University
- Phillip H. Hwang
- Department of Anatomy and Neurobiology, Boston University School of Medicine
- Justin A. Cramer
- Department of Radiology, College of Medicine, University of Nebraska Medical Center
- Brigid C. Dwyer
- Department of Neurology, Boston University School of Medicine
- Honglin Hao
- Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
- Michelle C. Kaku
- Department of Neurology, Boston University School of Medicine
- Sachin Kedar
- Department of Neurological Sciences, College of Medicine, University of Nebraska Medical Center
- Peter H. Lee
- Department of Radiology, Lahey Hospital & Medical Center
- Asim Z. Mian
- Department of Radiology, Boston University School of Medicine
- Daniel L. Murman
- Department of Neurological Sciences, College of Medicine, University of Nebraska Medical Center
- Sarah O’Shea
- Department of Neurology, Boston University School of Medicine
- Aaron B. Paul
- Department of Radiology, Lahey Hospital & Medical Center
- Marie-Helene Saint-Hilaire
- Department of Neurology, Boston University School of Medicine
- E. Alton Sartor
- Department of Neurology, Boston University School of Medicine
- Aneeta R. Saxena
- Department of Neurology, Boston University School of Medicine
- Ludy C. Shih
- Department of Neurology, Boston University School of Medicine
- Juan E. Small
- Department of Radiology, Lahey Hospital & Medical Center
- Maximilian J. Smith
- Department of Radiology, Lahey Hospital & Medical Center
- Arun Swaminathan
- Department of Neurological Sciences, College of Medicine, University of Nebraska Medical Center
- Courtney E. Takahashi
- Department of Neurology, Boston University School of Medicine
- Olga Taraschenko
- Department of Neurological Sciences, College of Medicine, University of Nebraska Medical Center
- Hui You
- Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
- Jing Yuan
- Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
- Yan Zhou
- Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
- Shuhan Zhu
- Department of Neurology, Boston University School of Medicine
- Michael L. Alosco
- Department of Neurology, Boston University School of Medicine
- Jesse Mez
- The Framingham Heart Study, Boston University School of Medicine
- Thor D. Stein
- Boston University Alzheimer’s Disease Research Center
- Kathleen L. Poston
- Department of Neurology, Stanford University
- Rhoda Au
- Department of Anatomy and Neurobiology, Boston University School of Medicine
- Vijaya B. Kolachalama
- Department of Medicine, Boston University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-31037-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
Here the authors present a deep learning framework for dementia diagnosis, which can identify persons with normal cognition, mild cognitive impairment, Alzheimer’s disease, and dementia due to other etiologies.
