Development of an Electrochemical Sensor Based on Nanocomposite of Fe₃O₄@SiO₂ and Multiwalled Carbon Nanotubes for Determination of Tetracycline in Real Samples

Abstract

In this work, an electrochemical sensor (GCE/MWCNT/Fe3O4@SiO2) based on a composite of multiwalled carbon nanotubes (MWCNT) and an Fe3O4@SiO2 (MMN) nanocomposite on a glassy carbon electrode (GCE) was developed for the detection of tetracycline (TC). The composite formed promoted an increased electrochemical signal and the stability of the sensor, combining its individual characteristics such as high electrical conductivity and large surface area. The composite material was characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Mössbauer spectroscopy, and scanning electron microscope (SEM). The adsorptive stripping differential pulse voltammetry (AdSDPV) promoted better performance for the electrochemical sensor and greater sensitivity for TC detection. Under optimized conditions, the currents increased linearly with TC concentrations from 4.0 to 36 µmol L−1 (0.997) and from 40 to 64 µmol L−1 (0.994) with detection and quantification limits of 1.67 µmol L−1 and 4.0 µmol L−1, respectively. The sensor was applied in the analysis of milk and river water samples, obtaining recovery values ranging from 91–117%.

Keywords

• electrochemical sensor
• multiwalled carbon nanotubes
• nanocomposite of Fe₃O₄@SiO₂
• tetracycline
• water samples
• milk samples