Communications Materials (Jan 2022)

Fast and real-time electrical transistor assay for quantifying SARS-CoV-2 neutralizing antibodies

  • Francesco Decataldo,
  • Laura Grumiro,
  • Maria Michela Marino,
  • Francesca Faccin,
  • Catia Giovannini,
  • Martina Brandolini,
  • Giorgio Dirani,
  • Francesca Taddei,
  • Davide Lelli,
  • Marta Tessarolo,
  • Maria Calienni,
  • Carla Cacciotto,
  • Antonio Lavazza,
  • Beatrice Fraboni,
  • Alessandra Scagliarini,
  • Vittorio Sambri

DOI
https://doi.org/10.1038/s43246-022-00226-6
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 9

Abstract

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The COVID-19 pandemic highlights the importance of tests for assessing antibody titer, such as for determining vaccine efficacy. Here, a fast-operating organic electrochemical transistor is shown to assess the cytopathic effect caused by the SARS CoV-2 virus on Vero E6 cells in real-time.