DIAGNOSTIC METHODS FOR MYOCARDIAL FIBROSIS

Abstract

Background. Myocardial fibrosis is a global public health problem because it is associated with almost all forms of cardiovascular diseases. Timely detection of myocardial fibrosis is an urgent task contributing to improving the quality of patients' life with socially significant diseases. The aim of the article is to systematize the methods of myocardial fibrosis diagnostics. Materials and methods. The review is performed on the basis of the analytical study methods in the diagnosis of fibrosis in myocardial infarction, coronary heart disease, hypertensive heart disease, cardiomyopathies, arrhythmias, atrial fibrillation. Analysis of fibrosis diagnostic methods included identification of the measurable value used to assess the type and localization of fibrosis, the decisive rule to assess the presence and extent of myocardial lesion, the features and limitations of the methods, as well as the evaluation of performance criteria (sensitivity, specificity). Results. The systematization of methods for fibrosis diagnostics, such as endomyocardial biopsy, coronary angiography, magnetic resonance imaging with contrast, multispiral computed tomography, perfusion scintigraphy, biomarkers, echocardiography and electrocardiography is presented. An algorithm for diagnosing myocardial fibrosis has been developed within the framework of the computer diagnostic system "Cardiovid". Conclusions. The performed review and the presented review, analysis, systematization allow to evaluate objectively the possibilities of the existing methods of diagnostics myocardial fibrosis. The development of minimally invasive or noninvasive diagnostic methods to improve their sensitivity and specificity is essential for fibrosis screening.

Keywords

• fibrosis
• myocardium
• cardiovascular diseases
• diagnostic methods
• review
• analysis
• systematization