Мать и дитя в Кузбассе (Feb 2020)
THE AVAILABILITY OF VITAMIN D IN CHILDREN FIRST YEAR WITH COW'S MILK PROTEINS ALLERGY LIVING IN CONDITIONS OF MILITARY CONFLICT IN THE DONBASS
Abstract
The aim of the research. To study the provision of vitamin D in infants, suffering from cow's milk proteins allergy and living in the Donbass in a military conflict. Materials and methods. 105 infants living in the Donetsk People's Republic suffering from cow's milk proteins allergy were examined. Diagnosis of allergy was based on anamnesis, objective examination and the results of diagnostic elimination diet. The level of vitamin D in serum in these patients was studied in all patients by determining serum levels of 25(OH)D. Results. Insufficient vitamin D levels were found in 57.1 ± 4.8 % infants with cow's milk proteins allergy, which was significantly higher (p < 0.05) compared to healthy children. Vitamin D deficiency was registered in 6.7 ± 2.4 % patients. Normal levels of vitamin D were established only in 36.2 ± 4.7 % in patients with cow's milk proteins allergy, which was statistically significant (p < 0.05) below compared to healthy children. Conclusion. Infants, suffering from cow's milk proteins allergy and living in the Donetsk People's Republic in a long-term military conflict, are characterized by a decrease in vitamin D, which may play a role in the formation of the immune response, the development of clinical manifestations of pathology and disrupt the development of secondary food tolerance to the allergens.
