Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity

Axel H. Newton; Andrew J. Pask

doi:10.1038/s42003-020-01501-3

Communications Biology (Dec 2020)

Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity

Axel H. Newton,
Andrew J. Pask

Affiliations

Axel H. Newton: Biosciences 4, The School of Biosciences, The University of Melbourne
Andrew J. Pask: Biosciences 4, The School of Biosciences, The University of Melbourne

DOI: https://doi.org/10.1038/s42003-020-01501-3
Journal volume & issue: Vol. 3, no. 1
pp. 1 – 9

Abstract

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In this Perspective, Axel Newton and Andrew Pask examine the role of the Runt-related transcription factor 2 (RUNX2) QA repeat during skeletal development and discuss how its emergence and expansion may have facilitated the evolution of morphological novelty in vertebrates.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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