GC–MS based metabolite profiling, antioxidant and antiurolithiatic properties of apple cider vinegar

Abstract

Aim: To perform in vitro analysis of antioxidant and antiurolithiasis to carry out GC–MS-based metabolite profile. Materials & methods: The effect of apple cider vinegar (ACV) in vitro, antioxidant and GC–MS analysis was evaluated. The antioxidant studies were performed. In vitro techniques included nucleation, aggregation and growth assay. Results & conclusion: The presence of polyphenols, flavonoids, alkaloids and carbohydrates was shown. Concentrations from 5–30 μg/ml could dissolve calcium oxalate (p < 0.05) in vitro. The IC50 value of ACV in DPPH was found to be around 7 μg/ml and the IC50 value of the ACV in ABTS assay was around 9 μg/ml. Different phytocompounds were obtained from GC–MS analysis. ACV can be consumed to prevent kidney stones which seems helpful to the current therapy.

Keywords

• antioxidant
• antiurolithiatic
• apple cider vinegar
• DPPH
• phytochemical constituents