Data in Brief (Sep 2016)

Mass spectrometry based data of the blister fluid proteome of paediatric burn patients

  • Tuo Zang,
  • Daniel A. Broszczak,
  • Leila Cuttle,
  • James A. Broadbent,
  • Catherine Tanzer,
  • Tony J. Parker

Journal volume & issue
Vol. 8
pp. 1099 – 1110

Abstract

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The data presented here are associated with the article “The blister fluid proteome of paediatric burns” (Zang et al., 2016) [1]. Burn injury is a highly traumatic event for children. The degree of burn severity (superficial-, deep-, or full-thickness injury) often dictates the extent of later scar formation which may require long term surgical operation or skin grafting. The data were obtained by fractionating paediatric burn blister fluid samples, which were pooled according to burn depth and then analysed using data dependent acquisition LC–MS/MS. The data includes a table of all proteins identified, in which burn depth category they were found, the percentage sequence coverage for each protein and the number of high confidence peptide identifications for each protein. Further Gene Ontology enrichment analysis shows the significantly over-represented biological processes, molecular functions, and cellular components of the burn blister fluid proteome. In addition, tables include the proteins associated with the biological processes of “wound healing” and “response to stress” as examples of highly relevant processes that occur in burn wounds.