Treatment of chronic viral hepatitis C with direct acting antiviral agent: review

Abstract

HCV infection treatment regimens are viewed from positions of HCV life cycle and replication, effects of NS3/4A protease inhibitors and NS5A/NS5B inhibitors on HCV strain replication. Evolution of HCV treatment regimens from its discovery to modern DAA agents had led to substantial progress although drug resistance poses a new issue to be addressed.

Keywords

• review
• antiviral therapy
• daa
• viral resistance