On the relationship between innate and adaptive immunity in psoriasis

Abstract

There is an overview of the current literature data, which reflects the key aspects of the etiology and pathogenesis of psoriasis. A genetically determined, multifactorial nature of the dermatosis was displayed. There were summarized numerous domestic and foreign data on immunological (cellular, humoral, mediator, extravasation, angiogenesis) and non-immune mechanisms of genesis of psoriasis.

Keywords

• adhesion molecule
• cytokines
• etiology
• keratinocytes
• pathogenesis