Scientific Reports (Nov 2021)

Efficacy on radiofrequency ablation according to the types of benign thyroid nodules

  • Jianhua Li,
  • Wenping Xue,
  • Pengfei Xu,
  • Zhen Deng,
  • Caiwen Duan,
  • Danhua Zhang,
  • Shouhua Zheng,
  • Kefei Cui,
  • Xinguang Qiu

DOI
https://doi.org/10.1038/s41598-021-01593-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Abstract Percutaneous radiofrequency ablation (RFA) has been recommended as minimally invasive treatment for patients with symptomatic benign thyroid nodules (BTNs) because of the large number of clinical applications. This retrospective observational study sought to evaluate the clinical outcomes of RFA for BTNs. From 2014 to 2019, a sample size of 1289 patients treated by RFA were 262 ones with solid nodules and 1027 ones with cystic-solid nodule, respectively. The efficacy including the nodule maximal diameter reduction ratio (MDRR), the volume reduction ratio (VRR) and the cosmetic scores reduction ratio (CSRR). The results of the nodule MDRR and VRR in the cystic-solid nodule group were significantly better than those in the solid nodule group at the 3rd and 6th month, and the CSRR in the two groups showed statistically significant difference at the 3rd month. In a word, RFA is an effective method for symptomatic benign solid or cystic-solid nodules. The achieved MDRR and VRR in the cystic-solid nodule group were significantly better than those in the solid nodule group at the 3rd and 6th month.