Restoration of brain dystrophin using tricyclo-DNA ASOs restores neurobehavioral deficits in DMD mice

• Muthukumar Karuppasamy,
• Matthew S. Alexander

Affiliations

Muthukumar Karuppasamy

Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children’s of Alabama, Birmingham, AL 35294, USA

Matthew S. Alexander

Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children’s of Alabama, Birmingham, AL 35294, USA; UAB Center for Exercise Medicine at the University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Genetics at the University of Alabama at Birmingham, Birmingham, AL 35294, USA; UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, AL 35233, USA; UAB Center for Neurodegeneration and Experimental Therapeutics (CNET), Birmingham, AL 35294, USA; Corresponding author: Matthew S. Alexander, Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children’s of Alabama, Birmingham, AL 35294, USA.