Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity

Henry W. Kietzman; Gracy Trinoskey-Rice; Sarah A. Blumenthal; Jidong D. Guo; Shannon L. Gourley

doi:10.1038/s41467-022-32388-9

Nature Communications (Aug 2022)

Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity

Henry W. Kietzman,
Gracy Trinoskey-Rice,
Sarah A. Blumenthal,
Jidong D. Guo,
Shannon L. Gourley

Affiliations

Henry W. Kietzman: Medical Scientist Training Program, Emory University School of Medicine
Gracy Trinoskey-Rice: Department of Pediatrics, Emory University School of Medicine
Sarah A. Blumenthal: Department of Psychiatry, Emory University School of Medicine
Jidong D. Guo: Emory National Primate Research Center, Emory University
Shannon L. Gourley: Department of Pediatrics, Emory University School of Medicine

DOI: https://doi.org/10.1038/s41467-022-32388-9
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

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Social experiences influence future decision making. The authors here establish a method for quantifying this phenomenon in mice and identify an amygdalo-frontal-striatal circuit controlling how social context shapes decisions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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