Polymers (Oct 2022)

Silicon-Based Scaffold for Wound Healing Skin Regeneration Applications: A Concise Review

  • Izzat Zulkiflee,
  • Syafira Masri,
  • Mazlan Zawani,
  • Atiqah Salleh,
  • Ibrahim Nor Amirrah,
  • Mohd Farhanulhakim Mohd Razip Wee,
  • Salma Mohamad Yusop,
  • Mh Busra Fauzi

DOI
https://doi.org/10.3390/polym14194219
Journal volume & issue
Vol. 14, no. 19
p. 4219

Abstract

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Silicon has made its breakthrough in various industries, including clinical and biomedical applications. Silicon-based biomaterials that were fabricated into various types of scaffolds may attract interest due to their highly favorable properties covering their excellent biocompatibility, high surface area, mechanical strength, and selectivity depending on their application including film, hydrogel, nanoparticles, and so on. Silicon-based materials have also shown exciting results involving cell culture, cell growth, as well as tissue engineering. In this article, a simple review compromising the evaluation of silicon’s unique properties has been discussed and followed by the application of the silicone-based product in future perspectives in biomedical fields. The review goals are to widen and inspire broader interest in silicone-based materials in wound healing research.

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