Nature Communications (Jul 2020)

Transcriptional activity and strain-specific history of mouse pseudogenes

  • Cristina Sisu,
  • Paul Muir,
  • Adam Frankish,
  • Ian Fiddes,
  • Mark Diekhans,
  • David Thybert,
  • Duncan T. Odom,
  • Paul Flicek,
  • Thomas M. Keane,
  • Tim Hubbard,
  • Jennifer Harrow,
  • Mark Gerstein

DOI
https://doi.org/10.1038/s41467-020-17157-w
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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Pseudogenes are key markers of genome remodelling processes. Here the authors present genome-wide annotation of the pseudogenes in the mouse reference genome and 18 inbred mouse strains, update human pseudogene annotations, and characterise the transcription and evolution of mouse pseudogenes.