The conservation of human functional variants and their effects across livestock species

Rongrong Zhao; Andrea Talenti; Lingzhao Fang; Shuli Liu; George Liu; Neil P. Chue Hong; Albert Tenesa; Musa Hassan; James G. D. Prendergast

doi:10.1038/s42003-022-03961-1

Communications Biology (Sep 2022)

The conservation of human functional variants and their effects across livestock species

Rongrong Zhao,
Andrea Talenti,
Lingzhao Fang,
Shuli Liu,
George Liu,
Neil P. Chue Hong,
Albert Tenesa,
Musa Hassan,
James G. D. Prendergast

Affiliations

Rongrong Zhao: The Roslin Institute, University of Edinburgh, Easter Bush Campus
Andrea Talenti: The Roslin Institute, University of Edinburgh, Easter Bush Campus
Lingzhao Fang: The Roslin Institute, University of Edinburgh, Easter Bush Campus
Shuli Liu: Westlake Laboratory of Life Sciences and Biomedicine
George Liu: Animal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, Agricultural Research Service, USDA
Neil P. Chue Hong: EPCC, Bayes Centre
Albert Tenesa: The Roslin Institute, University of Edinburgh, Easter Bush Campus
Musa Hassan: The Roslin Institute, University of Edinburgh, Easter Bush Campus
James G. D. Prendergast: The Roslin Institute, University of Edinburgh, Easter Bush Campus

DOI: https://doi.org/10.1038/s42003-022-03961-1
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

Read online

An investigation of genetic variants that exist across human and livestock species supports the clear potential of livestock models in providing insights into the mechanisms driving human diseases and traits.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal